ITGA4 Antikörper
Kurzübersicht für ITGA4 Antikörper (ABIN7013910)
Target
Alle ITGA4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Ms LPAM-1 Purified Azide Free
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Produktmerkmale
- The rat monoclonal antibody DATK32 recognizes an extracellular epitope of integrin alpha 4 (CD49d) and integrin beta7 (Ly69) components of mouse LPAM-1 complex, which is expressed on the majority of peripheral lymphocytes, as well as on subsets of thymocytes and bone marrow cells.
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Aufreinigung
- Purified by protein-G affinity chromatography.
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Immunogen
- TK1 cells
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Functional application: Blocking of cell adhesion.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4
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Konservierungsmittel
- Azide free
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- ITGA4 (Integrin alpha 4 (ITGA4))
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Andere Bezeichnung
- LPAM-1
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Hintergrund
- Integrin alpha 4 / beta 7 (CD49d / Ly69) , also known as LPAM-1 (Llmphocyte Peyer´s patch adhesion molecule 1), is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer´s patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion.,Integrin alpha 4 beta 7, CD49d / Ly69
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Gen-ID
- 35
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Pathways
- Integrin Complex
Target
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