TEK Antikörper (AA 571-748)
Kurzübersicht für TEK Antikörper (AA 571-748) (ABIN7193241)
Target
Alle TEK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 571-748
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Verwendungszweck
- CD202B Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CD202B (AA: 571-748) expressed in E. Coli.
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Isotyp
- IgG2b
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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Andere Bezeichnung
- CD202B
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Hintergrund
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This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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Molekulargewicht
- 125.8 kDa,
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UniProt
- Q02763
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Pathways
- RTK Signalweg, Growth Factor Binding
Target
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