MED14 Antikörper

Produktnummer ABIN7191443

Der Kaninchen Polyklonal Anti-MED14-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, MED14 in Proben von Human zu detektieren.

Kurzübersicht für MED14 Antikörper (ABIN7191443)

Target: MED14 (Mediator Complex Subunit 14 (MED14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED14 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-MED14 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human MED14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MED14

Target: MED14 (Mediator Complex Subunit 14 (MED14))

Andere Bezeichnung: MED14

Hintergrund:

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

Aliases: Activator-recruited cofactor 150 kDa component antibody, ARC150 antibody, Cofactor required for Sp1 transcriptional activation subunit 2 antibody, CRSP complex subunit 2 antibody, DRIP150 antibody, EXLM1 antibody, hRGR1 antibody, MED14 antibody, MED14_HUMAN antibody, Mediator complex subunit 14 antibody, Mediator of RNA polymerase II transcription subunit 14 antibody, RGR1 antibody, RGR1 homolog antibody, Thyroid hormone receptor-associated protein complex 170 kDa component antibody, Transcriptional coactivator CRSP150 antibody, Trap170 antibody, Vitamin D3 receptor-interacting protein complex 150 kDa component antibody

UniProt: O60244

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha