LILRB3 Antikörper

Produktnummer ABIN7191279

Dieses Anti-LILRB3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LILRB3 in ELISA und IHC. Geeignet für Human.

Kurzübersicht für LILRB3 Antikörper (ABIN7191279)

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LILRB3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-LILRB3 Antikörper

Verwendungszweck: LILRB3 Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human LILRB3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu LILRB3

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Andere Bezeichnung: LILRB3

Hintergrund:

Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases: LILRB3 antibody, ILT5 antibody, LIR3 antibody, Leukocyte immunoglobulin-like receptor subfamily B member 3 antibody, LIR-3 antibody, Leukocyte immunoglobulin-like receptor 3 antibody, CD85 antigen-like family member A antibody, Immunoglobulin-like transcript 5 antibody, ILT-5 antibody, Monocyte inhibitory receptor HL9 antibody, CD antigen CD85a antibody

UniProt: O75022