LILRB3 Antikörper (AA 400-500)

Produktnummer ABIN7268239

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LILRB3 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für LILRB3 Antikörper (AA 400-500) (ABIN7268239)

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LILRB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LILRB3 Antikörper

Bindungsspezifität: AA 400-500

Verwendungszweck: LILRB3 Rabbit pAb

Sequenz: RSSNPHLLSF PSEPLELMVS GHSGGSSLPP TGPPSTPGGP EDQPLNPPGS GPQNGLGRYL EVLIGVSVAF VLLLFLLLFL LLLRQRHSKH RTSDQRKTDF Q

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human LILRB3 (NP_001307889.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LILRB3

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Andere Bezeichnung: LILRB3

Hintergrund: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.,LILRB3,CD85A,HL9,ILT-5,ILT5,LILRA6,LIR-3,LIR3,PIR-B,PIRB,Immunology & Inflammation,CD markers,B Cell Receptor Signaling Pathway,LILRB3

Molekulargewicht: 69kDa/71kDa

Gen-ID: 11025

UniProt: O75022