CUX1 Antikörper (N-Term)

Produktnummer ABIN7184441

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CUX1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CUX1 Antikörper (N-Term) (ABIN7184441)

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CUX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CUX1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CUX1 Antibody

Kreuzreaktivität: Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human CUTL1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CUX1

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Andere Bezeichnung: CUX1

Hintergrund:

Background: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor, binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer, may require the basic helix-loop-helix protein TCF4 as a coactivator By similarity.

Neufeld E.J., Nat. Genet. 1:50-55(1992).
Gloeckner G., Genome Res. 8:1060-1073(1998).
Rong Zeng W., Gene 241:75-85(2000).

Aliases: CUX1 antibody, CUTL1Homeobox protein cut-like 1 antibody, CCAAT displacement protein antibody, CDP antibody, Homeobox protein cux-1 antibody

UniProt: P39880

Pathways: Cellular Glucan Metabolic Process