CLIC4 Antikörper (N-Term)

Produktnummer ABIN7184432

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CLIC4 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CLIC4 Antikörper (N-Term) (ABIN7184432)

Target: CLIC4 (Chloride Intracellular Channel 4 (CLIC4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLIC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-CLIC4 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human CLIC4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CLIC4

Target: CLIC4 (Chloride Intracellular Channel 4 (CLIC4))

Andere Bezeichnung: CLIC4

Hintergrund:

Background: Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH . Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).

Wiemann S., Genome Res. 11:422-435(2001).
Edwards J.C., Am. J. Physiol. 276:F398-F408(1999).
Chuang J.Z., J. Neurosci. 19:2919-2928(1999).

Aliases: Chloride intracellular channel 4 antibody, Chloride intracellular channel 4 (mitochondrial) antibody, Chloride intracellular channel 4 like antibody, Chloride intracellular channel protein 4 antibody, Clic4 antibody, CLIC4_HUMAN antibody, CLIC4L antibody, DKFZP566G223 antibody, FLJ38640 antibody, H1 antibody, HUH1 antibody, Intracellular chloride ion channel protein p64H1 antibody, MC3S5 antibody, mtCLIC antibody, p64H1 antibody

UniProt: Q9Y696