ARHGEF11 Antikörper (N-Term)

Produktnummer ABIN7184414

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ARHGEF11 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ARHGEF11 Antikörper (N-Term) (ABIN7184414)

Target: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ARHGEF11 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ARHGEF11 Antibody

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human ARHGEF11.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ARHGEF11

Target: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Andere Bezeichnung: ARHGEF11

Hintergrund:

Background: May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.

Nagase T., DNA Res. 4:141-150(1997).
Gregory S.G., Nature 441:315-321(2006).
Ruemenapp U., FEBS Lett. 459:313-318(1999).

Aliases: ARHGB_HUMAN antibody, ARHGEF 11 antibody, ARHGEF11 antibody, DKFZp667F1223 antibody, Glutamate transporter EAAT4 associated protein 48 antibody, GTRAP 48 antibody, GTRAP48 antibody, KIAA0380 antibody, OTTHUMP00000038716 antibody, OTTHUMP00000038717 antibody, PDZ RHOGEF antibody, PDZ-RhoGEF antibody, Rho guanine exchange factor (GEF) 11 antibody, Rho guanine nucleotide exchange factor (GEF) 11 antibody, Rho guanine nucleotide exchange factor 11 antibody, RhoA specific guanine nucleotide exchange factor antibody, RhoGEF glutamate transport modulator antibody

UniProt: O15085

Pathways: Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling