ELL Antikörper
Kurzübersicht für ELL Antikörper (ABIN7183500)
Target
Alle ELL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from internal of Human ELL.
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:3000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ELL (Elongation Factor RNA Polymerase II (ELL))
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Andere Bezeichnung
- ELL
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Hintergrund
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Background: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.
Thirman M.J., Proc. Natl. Acad. Sci. U.S.A. 91:12110-12114(1994).
Simone F., Blood 98:201-209(2001).
Kong S.E., Proc. Natl. Acad. Sci. U.S.A. 102:10094-10098(2005).Aliases: ELL antibody, C19orf17RNA polymerase II elongation factor ELL antibody, Eleven-nineteen lysine-rich leukemia protein antibody
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UniProt
- P55199
Target
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