ADRA2B Antikörper

Produktnummer ABIN7183076

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ADRA2B in ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ADRA2B Antikörper (ABIN7183076)

Target: ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA2B Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-ADRA2B Antikörper

Kreuzreaktivität: Human

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human Adrenergic Receptor alpha-2B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF:1:100-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ADRA2B

Target: ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))

Andere Bezeichnung: ADRA2B

Hintergrund:

Background: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.

Lomasney J.W., Proc. Natl. Acad. Sci. U.S.A. 87:5094-5098(1990).
Weinshank R.L., Mol. Pharmacol. 38:681-688(1990).
Small K.M., J. Biol. Chem. 276:4917-4922(2001).

Aliases: ADRA2B antibody, ADRA2L1 antibody, ADRA2RL1Alpha-2B adrenergic receptor antibody, Alpha-2 adrenergic receptor subtype C2 antibody, Alpha-2B adrenoreceptor antibody, Alpha-2B adrenoceptor antibody, Alpha-2BAR antibody

UniProt: P18089

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process