GRM8 Antikörper

Produktnummer ABIN7181343

Der Kaninchen Polyklonal Anti-GRM8 Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, GRM8 in Proben von Human zu detektieren.

Kurzübersicht für GRM8 Antikörper (ABIN7181343)

Target: GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRM8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-GRM8 Antikörper

Verwendungszweck: GRM8 Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Human GluR8.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GRM8

Target: GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

Andere Bezeichnung: GRM8

Hintergrund:

Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Patrick. M. Downey, J Biomol Screen, Dec 2005, 10: 841 - 848.
RJ Wenthold, J. Biol. Chem., Jan 1994, 269: 1332 - 1339.
Toshiaki Watanabe, Cancer Res., Oct 2006, 66: 9804 - 9808.
V. Bruno, J. Neurosci., Sep 2000, 20: 6413.

Aliases: FLJ41058 antibody, GLUR8 antibody, Glutamate receptor metabotropic 8 antibody, GPRC1H antibody, GRM8 antibody, GRM8_HUMAN antibody, Metabotropic glutamate receptor 8 antibody, MGC126724 antibody, mGlu8 antibody, mGluR8 antibody

UniProt: O00222

Pathways: cAMP Metabolic Process, Synaptic Membrane