CHRNA10 Antikörper (C-Term)

Produktnummer ABIN7180140

Der Kaninchen Polyklonal Anti-CHRNA10-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CHRNA10 in Proben von Human zu detektieren.

Kurzübersicht für CHRNA10 Antikörper (C-Term) (ABIN7180140)

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CHRNA10 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CHRNA10 Antibody

Kreuzreaktivität: Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human CHRNA10.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CHRNA10

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Andere Bezeichnung: CHRNA10

Hintergrund:

Background: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Sgard F., Mol. Pharmacol. 61:150-159(2002).
Lustig L.R., Genomics 73:272-283(2001).
Vandenberk I., Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.

Aliases: Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit antibody, ACH10_HUMAN antibody, Alpha 10 nAChR antibody, Cholinergic receptor nicotinic alpha 10 antibody, Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10 antibody, Cholinergic receptor, nicotinic, alpha polypeptide 10 antibody, CHRNA 10 antibody, CHRNA10 antibody, NACHR alpha 10 antibody, NACHR alpha-10 antibody, NACHRA10 antibody, Neuronal acetylcholine receptor protein subunit alpha 10 antibody, Neuronal acetylcholine receptor subunit alpha-10 antibody, Nicotinic acetylcholine receptor subunit alpha 10 antibody, Nicotinic acetylcholine receptor subunit alpha-10 antibody, OTTHUMP00000013620 antibody

UniProt: Q9GZZ6

Pathways: Sensory Perception of Sound, Synaptic Membrane