CDCA2 Antikörper (C-Term)

Produktnummer ABIN7180137

Der Kaninchen Polyklonal Anti-CDCA2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CDCA2 in Proben von Human zu detektieren.

Kurzübersicht für CDCA2 Antikörper (C-Term) (ABIN7180137)

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDCA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CDCA2 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human CDCA2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CDCA2

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Andere Bezeichnung: CDCA2

Hintergrund:

Background: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.

Walker M.G., Curr. Cancer Drug Targets 1:73-83(2001).
Ota T., . Genet. 36:40-45(2004).
Olsen J.V., Cell 127:635-648(2006).

Aliases: CDCA2Cell division cycle-associated protein 2 antibody, Recruits PP1 onto mitotic chromatin at anaphase protein antibody, Repo-Man antibody

UniProt: Q69YH5