SMAD1 Antikörper (Ser187)

Produktnummer ABIN7180082

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMAD1 in WB, ELISA, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SMAD1 Antikörper (Ser187) (ABIN7180082)

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMAD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SMAD1 Antikörper

Bindungsspezifität: Ser187

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human Smad1 around the phosphorylation site of serine 187 (P-H-S(p)-P-N).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SMAD1

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Andere Bezeichnung: SMAD1

Hintergrund:

Background:

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

Riggins G.J., Nat. Genet. 13:347-349(1996).
Liu F., Nature 381:620-623(1996).
Hoodless P.A., Cell 85:489-500(1996)

Aliases: BSP-1 antibody, BSP1 antibody, HsMAD1 antibody, JV4-1 antibody, JV41 antibody, MAD homolog 1 antibody, MAD mothers against decapentaplegic homolog 1 antibody, Mad related protein 1 antibody, Mad-related protein 1 antibody, MADH1 antibody, MADR1 antibody, Mothers against decapentaplegic homolog 1 antibody, Mothers against DPP homolog 1 antibody, SMA- AND MAD-RELATED PROTEIN 1 antibody, SMAD 1 antibody, SMAD family member 1 antibody, SMAD mothers against DPP homolog 1 antibody, Smad1 antibody, SMAD1_HUMAN antibody, TGF beta signaling protein 1 antibody, Transforming growth factor-beta-signaling protein 1 antibody

UniProt: Q15797

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development