MKNK1 Antikörper (Thr385)

Produktnummer ABIN7180049

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch MKNK1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MKNK1 Antikörper (Thr385) (ABIN7180049)

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MKNK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MKNK1 Antikörper

Bindungsspezifität: Thr385

Verwendungszweck: MKNK1 (Ab-385) Antibody

Kreuzreaktivität: Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human Mnk1 around the phosphorylation site of threonine 385 (L-P-T(p)-P-Q).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MKNK1

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Andere Bezeichnung: MKNK1

Hintergrund:

Background: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.

Fukunaga R., EMBO J. 16:1921-1933(1997).
Knauf U., Mol. Cell. Biol. 21:5500-5511(2001).
O'Loghlen A., Exp. Cell Res. 299:343-355(2004).

Aliases: MAP kinase interacting kinase 1 antibody, MAP kinase interacting serine/threonine kinase 1 antibody, MAP kinase signal integrating kinase 1 antibody, MAP kinase signal-integrating kinase 1 antibody, MAP kinase-interacting serine/threonine-protein kinase 1 antibody, MAPK signal integrating kinase 1 antibody, MITOGEN-ACTIVATED PROTEIN KINASE-INTERACTING SERINE/THREONINE KINASE 1 antibody, mknk1 antibody, MKNK1_HUMAN antibody, MNK 1 antibody, Mnk1 antibody

UniProt: Q9BUB5

Pathways: MAPK Signalweg, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor