APLP2 Antikörper (Tyr755)

Produktnummer ABIN7179975

Der Kaninchen-Polyklonal Anti-APLP2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet zum Nachweis von APLP2 in Proben aus Human. }

Kurzübersicht für APLP2 Antikörper (Tyr755) (ABIN7179975)

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APLP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-APLP2 Antikörper

Bindungsspezifität: Tyr755

Verwendungszweck: APLP2 (Ab-755) Antibody

Kreuzreaktivität: Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human APLP2 around the phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu APLP2

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Andere Bezeichnung: APLP2

Hintergrund:

Background: May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts By similarity.

Sprecher C.A., Biochemistry 32:4481-4486(1993).
Wasco W., Nat. Genet. 5:95-99(1993).
von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).

Aliases: amyloid beta (A4) precursor like protein 2 antibody, Amyloid like protein 2 antibody, Amyloid precursor protein homolog HSD 2 antibody, amyloid precursor protein homolog HSD2 antibody, Amyloid protein homolog antibody, Amyloid-like protein 2 antibody, APLP-2 antibody, Aplp2 antibody, APLP2_HUMAN antibody, APPH antibody, APPL2 antibody, CDEBP antibody, CDEI box binding protein antibody, CDEI box-binding protein antibody

UniProt: Q06481

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour