VCP Antikörper (AA 704-806) (Biotin)

Produktnummer ABIN7179883

Produktdetails anti-VCP Antikörper (Biotin)

Target: VCP (Valosin Containing Protein (VCP))

Bindungsspezifität: AA 704-806

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VCP Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Zebrafisch (Danio rerio)

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Zebrafish Transitional endoplasmic reticulum ATPase protein (704-806AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu VCP

Target: VCP (Valosin Containing Protein (VCP))

Andere Bezeichnung: vcp (VCP Produkte)

Synonyme: ALS14 antikoerper, IBMPFD antikoerper, TERA antikoerper, p97 antikoerper, CDC48 antikoerper, wu:fd16d05 antikoerper, wu:fj63d11 antikoerper, p93 antikoerper, 3110001E05 antikoerper, p97/VCP antikoerper, 22.26 antikoerper, 7.12 antikoerper, Apple antikoerper, BcDNA.GM02885 antikoerper, BcDNA:GM02885 antikoerper, CG2331 antikoerper, DmTER94 antikoerper, Dmel\CG2331 antikoerper, I antikoerper, Ter94 antikoerper, Tera antikoerper, VCP antikoerper, VCP ATPase antikoerper, VCP/p97 antikoerper, Vcp antikoerper, anon-WO2004063362.65 antikoerper, anon-WO2004063362.67 antikoerper, cdc48 antikoerper, dTERA antikoerper, dVCP antikoerper, dmTERA antikoerper, dvcp antikoerper, l(2)03775 antikoerper, l(2)46CFf antikoerper, l(2)46CFs antikoerper, l(2)46Ch antikoerper, pTER94 antikoerper, ter94 antikoerper, vcp antikoerper, FANCG antikoerper, valosin containing protein antikoerper, valosin containing protein S homeolog antikoerper, valosin-containing protein antikoerper, CG2331 gene product from transcript CG2331-RA antikoerper, zgc:136908 antikoerper, transitional endoplasmic reticulum ATPase antikoerper, VCP antikoerper, vcp.S antikoerper, vcp antikoerper, Vcp antikoerper, Bm1_56585 antikoerper, LOC100136246 antikoerper, TER94 antikoerper, zgc:136908 antikoerper, LOC101109680 antikoerper

Hintergrund:

Background: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Also involved in DNA damage response: recruited to double-strand breaks (DSBs) sites and promotes the recruitment of tp53bp1 at DNA damage sites (By similarity). Enhances cell cycle progression and inhibits apoptosis at low temperatures (PubMed:12914916). Essential for the maturation of ubiquitin-containing autophagosomes and the clearance of ubiquitinated protein by autophagy (By similarity). Acts as a negative regulator of type I interferon production by promoting ubiquitination of ddx58/rig-i (By similarity). May play a role in the ubiquitin-dependent sorting of membrane proteins to lysosomes where they undergo degradation (By similarity).

Aliases: vcp antibody, cdc48 antibody, si:ch211-113n10.2Transitional endoplasmic reticulum ATPase antibody, TER ATPase antibody, EC 3.6.4.6 antibody, Protein CDC48 antibody, Valosin-containing protein antibody, VCP antibody

UniProt: Q7ZU99

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway