SAA1 Antikörper

Produktnummer ABIN7179313

Dieses Anti-SAA1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von SAA1 in ELISA. Geeignet für Human.

Kurzübersicht für SAA1 Antikörper (ABIN7179313)

Target: SAA1 (Serum Amyloid A1 (SAA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SAA1 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 1F2E1

Produktdetails anti-SAA1 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Protein G purified

Immunogen: Recombinant Serum amyloid A-1 Protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 15mmol/L Sodium azide
Constituents: 0.1Mol/L Nacl

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SAA1

Target: SAA1 (Serum Amyloid A1 (SAA1))

Andere Bezeichnung: SAA1

Hintergrund:

Background: Serum amyloid A protein, also named SAA, Amyloid protein A, Amyloid fibril protein AA, SAA1, SAA2 and PIG4, is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 is produced mainly in the liver and circulates in low levels in the blood. SAA1 may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex. The SAA1 cleavage product a designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver, spleen, and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis, they disrupt tissue structure and compromise performance.

Aliases: SAA1, Serum amyloid A-1 protein, Amyloid fibril protein AA

UniProt: P0DJI8

Pathways: Toll-Like Receptors Cascades