SAA1 Antikörper

Produktnummer ABIN7252717

Produktdetails anti-SAA1 Antikörper

Target: SAA1 (Serum Amyloid A1 (SAA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAA1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human SAA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SAA1

Target: SAA1 (Serum Amyloid A1 (SAA1))

Andere Bezeichnung: SAA1 (SAA1 Produkte)

Synonyme: PIG4 antikoerper, SAA antikoerper, SAA2 antikoerper, TP53I4 antikoerper, zgc:103580 antikoerper, SAA1 antikoerper, Saa-1 antikoerper, Saa2 antikoerper, serum amyloid A1 antikoerper, serum amyloid A antikoerper, amyloid protein A antikoerper, serum amyloid A protein antikoerper, serum amyloid a protein antikoerper, serum amyloid A 1 antikoerper, serum amyloid protein A antikoerper, SAA1 antikoerper, saa antikoerper, LOC694827 antikoerper, Sden_2438 antikoerper, Mmc1_0571 antikoerper, Riean_0971 antikoerper, Saa1 antikoerper, LOC100009168 antikoerper, LOC101120204 antikoerper

Hintergrund: This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. SAA1 (Serum Amyloid A1) is a Protein Coding gene. Diseases associated with SAA1 include Amyloidosis Aa and Splenic Artery Aneurysm. Among its related pathways are Peptide ligand-binding receptors and Activated TLR4 signalling. GO annotations related to this gene include heparin binding and chemoattractant activity. An important paralog of this gene is SAA2.

UniProt: P0DJI8

Pathways: Toll-Like Receptors Cascades