MMP2 Antikörper (AA 110-662) (Biotin)
Kurzübersicht für MMP2 Antikörper (AA 110-662) (Biotin) (ABIN7178758)
Target
Alle MMP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 110-662
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Kreuzreaktivität
- Ratte
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Rat 72 kDa type IV collagenase protein (110-662AA)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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Andere Bezeichnung
- Mmp2
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Hintergrund
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Background: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues (By similarity).
Aliases: Mmp2 antibody, 72 kDa type IV collagenase antibody, EC 3.4.24.24 antibody, 72 kDa gelatinase antibody, Gelatinase A antibody, Matrix metalloproteinase-2 antibody, MMP-2) [Cleaved into: PEX] antibody
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UniProt
- P33436
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Pathways
- Activation of Innate immune Response
Target
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