UVSSA/KIAA1530 Antikörper (AA 143-206) (FITC)

Produktnummer ABIN7175184

Der Kaninchen Polyklonal Anti-UVSSA/KIAA1530-Antikörper wurde für validiert. Er ist geeignet, UVSSA/KIAA1530 in Proben von Human zu detektieren.

Kurzübersicht für UVSSA/KIAA1530 Antikörper (AA 143-206) (FITC) (ABIN7175184)

Target: UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UVSSA/KIAA1530 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-UVSSA/KIAA1530 Antikörper (FITC)

Bindungsspezifität: AA 143-206

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human UV-stimulated scaffold protein A protein (143-206AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu UVSSA/KIAA1530

Target: UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))

Andere Bezeichnung: UVSSA

Hintergrund:

Background: Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage.

Aliases: hypothetical protein LOC57654 antibody, K1530_HUMAN antibody, KIAA1530 antibody, Uncharacterized protein KIAA1530 antibody, UV stimulated scaffold protein A antibody, UVSS3 antibody, UVSSA antibody

UniProt: Q2YD98