RPS27A Antikörper (AA 16-56) (Biotin)

Produktnummer ABIN7174406

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RPS27A in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RPS27A Antikörper (AA 16-56) (Biotin) (ABIN7174406)

Target: RPS27A (Ribosomal Protein S27a (RPS27A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS27A Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-RPS27A Antikörper (Biotin)

Bindungsspezifität: AA 16-56

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin-40S ribosomal protein S27a protein (16-56AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RPS27A

Target: RPS27A (Ribosomal Protein S27a (RPS27A))

Andere Bezeichnung: RPS27A

Hintergrund:

Background: Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.

Aliases: RPS27A antibody, UBA80 antibody, UBCEP1 antibody, Ubiquitin-40S ribosomal protein S27a antibody, Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin, 40S ribosomal protein S27a antibody, Small ribosomal subunit protein eS31)] antibody

UniProt: P62979

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation