Transferrin Receptor Antikörper (AA 94-754) (FITC)

Produktnummer ABIN7172797

Dieses Anti-Transferrin Receptor-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Transferrin Receptor in . Geeignet für Human.

Kurzübersicht für Transferrin Receptor Antikörper (AA 94-754) (FITC) (ABIN7172797)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-Transferrin Receptor Antikörper (FITC)

Bindungsspezifität: AA 94-754

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Transferrin receptor protein 1 protein (94-754AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: TFRC

Hintergrund:

Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

Aliases: CD 71 antibody, CD71 antibody, CD71 antigen antibody, IMD46 antibody, OTTHUMP00000208523 antibody, OTTHUMP00000208524 antibody, OTTHUMP00000208525 antibody, p90 antibody, sTfR antibody, T9 antibody, TFR 1 antibody, TfR antibody, TfR1 antibody, TFR1_HUMAN antibody, TFRC antibody, TR antibody, Transferrin receptor (p90 CD71) antibody, Transferrin receptor protein 1, serum form antibody, Trfr antibody

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis