ZBTB33 Antikörper (AA 113-228) (Biotin)

Produktnummer ABIN7172776

Dieses Anti-ZBTB33-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ZBTB33 in ELISA. Geeignet für Human.

Kurzübersicht für ZBTB33 Antikörper (AA 113-228) (Biotin) (ABIN7172776)

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBTB33 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-ZBTB33 Antikörper (Biotin)

Bindungsspezifität: AA 113-228

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Transcriptional regulator Kaiso protein (113-228AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ZBTB33

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Andere Bezeichnung: ZBTB33

Hintergrund:

Background: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5\'-CGCG-3\' and also binds to the non-methylated consensus sequence 5\'-CTGCNA-3\' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453).

Aliases: Kaiso antibody, Kaiso protein antibody, Kaiso transcription factor antibody, KAISO_HUMAN antibody, Transcriptional regulator Kaiso antibody, ZBTB 33 antibody, Zbtb33 antibody, Zinc finger and BTB domain containing 33 antibody, Zinc finger and BTB domain-containing protein 33 antibody, Zinc finger transcription factor Kaiso antibody, ZNF 348 antibody, ZNF Kaiso antibody, ZNF348 antibody

UniProt: Q86T24