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RFX3 Antikörper (AA 201-413) (HRP)

This anti-RFX3 antibody (ABIN7172601) is a Rabbit Polyclonal antibody detecting RFX3 in ELISA. Suitable for Human.
Produktnummer ABIN7172601

Kurzübersicht für RFX3 Antikörper (AA 201-413) (HRP) (ABIN7172601)

Target

Alle RFX3 Antikörper anzeigen
RFX3 (Regulatory Factor X 3 (RFX3))

Reaktivität

  • 27
  • 8
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
Human

Wirt

  • 24
  • 3
Kaninchen

Klonalität

  • 26
  • 1
Polyklonal

Konjugat

  • 19
  • 3
  • 2
  • 1
  • 1
  • 1
Dieser RFX3 Antikörper ist konjugiert mit HRP

Applikation

  • 23
  • 15
  • 5
  • 4
  • 2
  • 1
  • 1
ELISA
  • Bindungsspezifität

    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-413

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Transcription factor RFX3 protein (201-413AA)

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    RFX3 (Regulatory Factor X 3 (RFX3))

    Andere Bezeichnung

    RFX3

    Hintergrund

    Background: Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes. Acts as a transcription factor. Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells.

    Aliases: bA32F11.1 antibody, DNA binding protein RFX3 antibody, Regulatory factor X 3 antibody, Regulatory factor X, 3 (influences HLA class II expression) antibody, RFX3 antibody, RFX3_HUMAN antibody, Transcription factor RFX3 antibody

    UniProt

    P48380
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