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MAFB Antikörper (AA 168-323) (FITC)

Der Kaninchen Polyklonal Anti-MAFB-Antikörper wurde für validiert. Er ist geeignet, MAFB in Proben von Human zu detektieren.
Produktnummer ABIN7172580

Kurzübersicht für MAFB Antikörper (AA 168-323) (FITC) (ABIN7172580)

Target

Alle MAFB Antikörper anzeigen
MAFB (Transcription Factor MafB (MAFB))

Reaktivität

  • 36
  • 14
  • 13
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 34
  • 2
Kaninchen

Klonalität

  • 33
  • 3
Polyklonal

Konjugat

  • 20
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MAFB Antikörper ist konjugiert mit FITC

Applikation

Bitte anfragen
  • Bindungsspezifität

    • 10
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 168-323

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Transcription factor MafB protein (168-323AA)

    Isotyp

    IgG
  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    MAFB (Transcription Factor MafB (MAFB))

    Andere Bezeichnung

    MAFB

    Hintergrund

    Background: Acts as a transcriptional activator or repressor (PubMed:27181683). Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.

    Aliases: Kreisler antibody, Kreisler (mouse) maf related leucine zipper homolog antibody, Kreisler maf related leucine zipper homolog antibody, KRML antibody, MAF bZIP transcription factor B antibody, Maf-B antibody, Mafb antibody, MAFB/Kreisler basic region/leucine zipper transcription factor antibody, MAFB_HUMAN antibody, MGC43127 antibody, Segmentation protein KR antibody, Transcription factor MafB antibody, V maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) antibody, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B antibody

    UniProt

    Q9Y5Q3
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