THO Complex 3 Antikörper (AA 2-351) (HRP)

Produktnummer ABIN7172054

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch THO Complex 3 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für THO Complex 3 Antikörper (AA 2-351) (HRP) (ABIN7172054)

Target: THO Complex 3 (THOC3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THO Complex 3 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-THO Complex 3 Antikörper (HRP)

Bindungsspezifität: AA 2-351

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human THO complex subunit 3 protein (2-351AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu THO Complex 3

Target: THO Complex 3 (THOC3)

Andere Bezeichnung: THOC3

Hintergrund:

Background: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

Aliases: hTREX45 antibody, TEX1 homolog antibody, THO complex subunit 3 antibody, Tho3 antibody, THOC3 antibody, THOC3_HUMAN antibody

UniProt: Q96J01