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THO Complex 3 Antikörper (AA 2-351) (HRP)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch THO Complex 3 in ELISA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7172054

Kurzübersicht für THO Complex 3 Antikörper (AA 2-351) (HRP) (ABIN7172054)

Target

Alle THO Complex 3 (THOC3) Antikörper anzeigen
THO Complex 3 (THOC3)

Reaktivität

  • 24
  • 7
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
Human

Wirt

  • 21
  • 3
Kaninchen

Klonalität

  • 22
  • 2
Polyklonal

Konjugat

  • 16
  • 3
  • 2
  • 1
  • 1
  • 1
Dieser THO Complex 3 Antikörper ist konjugiert mit HRP

Applikation

  • 19
  • 14
  • 6
  • 1
  • 1
  • 1
ELISA
  • Bindungsspezifität

    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-351

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human THO complex subunit 3 protein (2-351AA)

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    THO Complex 3 (THOC3)

    Andere Bezeichnung

    THOC3

    Hintergrund

    Background: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

    Aliases: hTREX45 antibody, TEX1 homolog antibody, THO complex subunit 3 antibody, Tho3 antibody, THOC3 antibody, THOC3_HUMAN antibody

    UniProt

    Q96J01
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