TINF2 Antikörper (AA 210-451)

Produktnummer ABIN7171778

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TINF2 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TINF2 Antikörper (AA 210-451) (ABIN7171778)

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TINF2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-TINF2 Antikörper

Bindungsspezifität: AA 210-451

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human TERF1-interacting nuclear factor 2 protein (210-451AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TINF2

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Andere Bezeichnung: TINF2

Hintergrund:

Background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.

Aliases: AW552114 antibody, D14Wsu146e antibody, DKCA3 antibody, MGC94711 antibody, TERF 1 (TRF 1) interacting nuclear factor 2 antibody, TERF 1 interacting nuclear factor 2 antibody, TERF1 (TRF1) interacting nuclear factor 2 antibody, TERF1 interacting nuclear factor 2 antibody, TERF1-interacting nuclear factor 2 antibody, Tin 2 antibody, TIN2 antibody, TINF 2 antibody, Tinf2 antibody, TINF2_HUMAN antibody, TRF 1 interacting nuclear factor 2 antibody, TRF1 interacting nuclear factor 2 antibody, TRF1-interacting nuclear protein 2 antibody

UniProt: Q9BSI4

Pathways: Zellzyklus, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process