CD86 Antikörper (AA 24-247)

Produktnummer ABIN7171453

Dieses Anti-CD86-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD86 in ELISA. Geeignet für Human.

Kurzübersicht für CD86 Antikörper (AA 24-247) (ABIN7171453)

Target: CD86

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD86 Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-CD86 Antikörper

Bindungsspezifität: AA 24-247

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human T-lymphocyte activation antigen CD86 protein (24-247AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CD86

Target: CD86

Andere Bezeichnung: CD86

Hintergrund:

Background: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B.

Aliases: Activation B7-2 antigen 3 antibody, Activation B7-2 antigen antibody, B-lymphocyte activation antigen B7-2 2 antibody, B-lymphocyte activation antigen B7-2 antibody, B7 2 antibody, B7 antibody, B7-2 antibody, B7.2 antibody, B70 antibody, B72 antibody, B72 antigen antibody, BU63 antibody, CD28 antigen ligand 2 2 antibody, CD28 antigen ligand 2 antibody, Cd28l2 antibody, CD28LG2 antibody, CD86 antibody, CD86 antigen (CD28 antigen ligand 2 B7 2 antigen) antibody, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2 antibody, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) antibody, CD86 antigen antibody, CD86 Molecule antibody, CD86_HUMAN antibody, CLS1 antibody, CTLA-4 counter-receptor B7.2 2 antibody, CTLA-4 counter-receptor B7.2 2, 3 antibody, CTLA-4 counter-receptor B7.2 antibody, Early T-cell costimulatory molecule 1 antibody, ETC-1 antibody, FUN 1 antibody, FUN-1 antibody, FUN1 antibody, LAB72 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, Membrane glycoprotein antibody, MGC34413 antibody, T lymphocyte activation antigen CD86 precursor antibody, T-lymphocyte activation antigen CD86 antibody, TS/A-2 antibody

UniProt: P42081

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation