SOCS2 Antikörper (AA 1-198) (Biotin)

Produktnummer ABIN7170997

Dieses Anti-SOCS2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SOCS2 in ELISA. Geeignet für Human.

Kurzübersicht für SOCS2 Antikörper (AA 1-198) (Biotin) (ABIN7170997)

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-SOCS2 Antikörper (Biotin)

Bindungsspezifität: AA 1-198

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Suppressor of cytokine signaling 2 protein (1-198AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SOCS2

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Andere Bezeichnung: SOCS2

Hintergrund:

Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Aliases: CIS 2 antibody, CIS-2 antibody, CIS2 antibody, Cish 2 antibody, Cish2 antibody, Cytokine inducible SH2 protein 2 antibody, Cytokine-inducible SH2 protein 2 antibody, SOCS 2 antibody, SOCS-2 antibody, Socs2 antibody, SOCS2_HUMAN antibody, SSI 2 antibody, SSI-2 antibody, SSI2 antibody, STAT induced STAT inhibitor 2 antibody, STAT-induced STAT inhibitor 2 antibody, STATI 2 antibody, STATI2 antibody, Suppressor of cytokine signaling 2 antibody

UniProt: O14508

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus