Stim2 Antikörper (AA 471-656) (Biotin)

Produktnummer ABIN7170838

Dieses Anti-Stim2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Stim2 in ELISA. Geeignet für Human.

Kurzübersicht für Stim2 Antikörper (AA 471-656) (Biotin) (ABIN7170838)

Target: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Stim2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-Stim2 Antikörper (Biotin)

Bindungsspezifität: AA 471-656

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Stromal interaction molecule 2 protein (471-656AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Stim2

Target: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Andere Bezeichnung: STIM2

Hintergrund:

Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx.

Aliases: FLJ39527 antibody, KIAA1482 antibody, STIM 2 antibody, STIM2 antibody, STIM2_HUMAN antibody, Stromal interaction molecule 2 antibody

UniProt: Q9P246

Pathways: T-Zell Rezeptor Signalweg, BCR Signaling