ESRRA Antikörper (AA 1-423)

Produktnummer ABIN7170761

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ESRRA in IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ESRRA Antikörper (AA 1-423) (ABIN7170761)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRRA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-ESRRA Antikörper

Bindungsspezifität: AA 1-423

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Steroid hormone receptor ERR1 protein (1-423AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Andere Bezeichnung: ESRRA

Hintergrund:

Background: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5\\\'-TNAAGGTCA-3\\\'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.

Aliases: Err 1 antibody, ERR a antibody, ERR alpha antibody, ERR-alpha antibody, Err1 antibody, ERR1 protein antibody, ERR1_HUMAN antibody, ERRa antibody, ERRalpha antibody, ESRL 1 antibody, ESRL1 antibody, ESRR A antibody, Esrra antibody, Estrogen receptor like 1 antibody, Estrogen receptor related 1 antibody, estrogen receptor related receptor alpha antibody, Estrogen receptor-like 1 antibody, Estrogen related receptor alpha antibody, Estrogen-related receptor alpha antibody, Estrra antibody, hERR1 antibody, NR3B1 antibody, Nuclear receptor subfamily 3 group B member 1 antibody, Steroid hormone receptor ERR1 antibody

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha