Splicing factor U2AF 26 kDa subunit (U2AF1L4) (AA 1-202) Antikörper

Produktnummer ABIN7170630

Der Kaninchen Polyklonal anti-Splicing factor U2AF 26 kDa subunit Antikörper wird verwendet zum Nachweis von Splicing factor U2AF 26 kDa subunit in Proben von Human. Er wurde validiert für ELISA und IHC.

Kurzübersicht für Splicing factor U2AF 26 kDa subunit (U2AF1L4) (AA 1-202) Antikörper (ABIN7170630)

Target: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: AA 1-202

Verwendungszweck: U2AF1L4 Antibody

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Splicing factor U2AF 26 kDa subunit protein (1-202AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Andere Bezeichnung: U2AF1L4

Hintergrund:

Background: RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3\\\'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3\\\'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity).

Aliases: FLJ35525 antibody, MGC33901 antibody, Splicing factor U2AF 26 kDa subunit antibody, U2 auxiliary factor 26 antibody, U2 small nuclear RNA auxiliary factor 1 like 3 antibody, U2 small nuclear RNA auxiliary factor 1 like 4 antibody, U2 small nuclear RNA auxiliary factor 1 like protein 3 antibody, U2 small nuclear RNA auxiliary factor 1 like protein 4 antibody, U2 small nuclear RNA auxiliary factor 1-like protein 3 antibody, U2 small nuclear RNA auxiliary factor 1-like protein 4 antibody, U2(RNU2) small nuclear RNA auxiliary factor 1 like 3 antibody, U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3 antibody, U2AF1 like protein 3 antibody, U2AF1 RS3 antibody, U2AF1-like protein 3 antibody, U2AF1L3V1 antibody, U2AF1L4 antibody, U2AF1RS3 antibody, U2af26 antibody, U2AF4_HUMAN antibody, U2RNU2 small nuclear RNA auxiliary factor 1 like 3 antibody, U2RNU2 small nuclear RNA auxiliary factor 1 like protein 3 antibody

UniProt: Q8WU68