Splicing factor U2AF 26 kDa subunit (U2AF1L4) (AA 1-202) Antikörper

Produktnummer ABIN7170630

Produktdetails

Target: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Bindungsspezifität: AA 1-202

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Splicing factor U2AF 26 kDa subunit protein (1-202AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Andere Bezeichnung: U2AF1L4 (U2AF1L4 Produkte)

Hintergrund:

Background: RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3\\\'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3\\\'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity).

Aliases: FLJ35525 antibody, MGC33901 antibody, Splicing factor U2AF 26 kDa subunit antibody, U2 auxiliary factor 26 antibody, U2 small nuclear RNA auxiliary factor 1 like 3 antibody, U2 small nuclear RNA auxiliary factor 1 like 4 antibody, U2 small nuclear RNA auxiliary factor 1 like protein 3 antibody, U2 small nuclear RNA auxiliary factor 1 like protein 4 antibody, U2 small nuclear RNA auxiliary factor 1-like protein 3 antibody, U2 small nuclear RNA auxiliary factor 1-like protein 4 antibody, U2(RNU2) small nuclear RNA auxiliary factor 1 like 3 antibody, U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3 antibody, U2AF1 like protein 3 antibody, U2AF1 RS3 antibody, U2AF1-like protein 3 antibody, U2AF1L3V1 antibody, U2AF1L4 antibody, U2AF1RS3 antibody, U2af26 antibody, U2AF4_HUMAN antibody, U2RNU2 small nuclear RNA auxiliary factor 1 like 3 antibody, U2RNU2 small nuclear RNA auxiliary factor 1 like protein 3 antibody

UniProt: Q8WU68