SSTR2 Antikörper (AA 304-369) (FITC)

Produktnummer ABIN7170311

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SSTR2 in . Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SSTR2 Antikörper (AA 304-369) (FITC) (ABIN7170311)

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSTR2 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-SSTR2 Antikörper (FITC)

Bindungsspezifität: AA 304-369

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Somatostatin receptor type 2 protein (304-369AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SSTR2

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Andere Bezeichnung: SSTR2

Hintergrund:

Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

Aliases: Somatostatin receptor type 2 antibody, SRIF-1 antibody, SRIF1 antibody, SS-2-R antibody, SS2-R antibody, SS2R antibody, SSR2_HUMAN antibody, SST2 antibody, SSTR2 antibody

UniProt: P30874