SCN9A Antikörper (AA 1849-1988)

Produktnummer ABIN7169929

Produktdetails anti-SCN9A Antikörper

Target: SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))

Bindungsspezifität: AA 1849-1988

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN9A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Sodium channel protein type 9 subunit alpha protein (1849-1988AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SCN9A

Target: SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))

Andere Bezeichnung: SCN9A (SCN9A Produkte)

Hintergrund:

Background: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:7720699, PubMed:17167479, PubMed:25240195, PubMed:26680203, PubMed:15385606, PubMed:16988069, PubMed:17145499, PubMed:19369487, PubMed:24311784). It is a tetrodotoxin-sensitive Na(+) channel isoform (PubMed:7720699). Plays a role in pain mechanisms, especially in the development of inflammatory pain (PubMed:17167479, PubMed:17145499, PubMed:19369487, PubMed:24311784).

Aliases: ETHA antibody, GEFSP7 antibody, hNE Na antibody, hNE-Na antibody, hNENa antibody, NE NA antibody, NENA antibody, Neuroendocrine sodium channel antibody, Peripheral sodium channel 1 antibody, PN1 antibody, Scn9a antibody, SCN9A_HUMAN antibody, Sodium channel protein type 9 subunit alpha antibody, Sodium channel protein type IX subunit alpha antibody, Sodium channel voltage gated type IX alpha antibody, Sodium channel voltage gated type IX alpha polypeptide antibody, Sodium channel voltage gated type IX alpha subunit antibody, Voltage gated sodium channel alpha subunit Nav1.7 antibody, Voltage gated sodium channel subunit alpha Nav1 antibody, Voltage-gated sodium channel subunit alpha Nav1.7 antibody

UniProt: Q15858