SUMO2 Antikörper (AA 1-84) (Biotin)

Produktnummer ABIN7169886

Der Kaninchen Polyklonal Anti-SUMO2-Antikörper wurde für ELISA validiert. Er ist geeignet, SUMO2 in Proben von Human zu detektieren.

Kurzübersicht für SUMO2 Antikörper (AA 1-84) (Biotin) (ABIN7169886)

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUMO2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-SUMO2 Antikörper (Biotin)

Bindungsspezifität: AA 1-84

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Small ubiquitin-related modifier 2 protein (1-84AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SUMO2

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Andere Bezeichnung: SUMO2

Hintergrund:

Background: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2, CBX4 or ZNF451 (PubMed:26524494). This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (PubMed:18408734, PubMed:18538659, PubMed:21965678, PubMed:9556629). Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744).

Aliases: HSMT 3 antibody, HSMT3 antibody, MGC117191 antibody, Sentrin 2 antibody, Sentrin-2 antibody, Sentrin2 antibody, Small ubiquitin like modifier 2 antibody, Small ubiquitin related modifier 2 antibody, Small ubiquitin-related modifier 2 antibody, SMT 3B antibody, SMT3 homolog 2 antibody, SMT3 suppressor of mif two 3 homolog 2 antibody, SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) antibody, SMT3, yeast, homolog 2 antibody, Smt3A antibody, SMT3B antibody, SMT3H2 antibody, SUMO-2 antibody, SUMO-3 antibody, SUMO2 antibody, SUMO2_HUMAN antibody, Sumo3 antibody, Ubiquitin like protein SMT3B antibody, Ubiquitin-like protein SMT3A antibody

UniProt: P61956

Pathways: Methionine Biosynthetic Process