PGAM5 Antikörper (AA 30-223) (Biotin)

Produktnummer ABIN7169301

Der Kaninchen Polyklonal Anti-PGAM5-Antikörper wurde für ELISA validiert. Er ist geeignet, PGAM5 in Proben von Human zu detektieren.

Kurzübersicht für PGAM5 Antikörper (AA 30-223) (Biotin) (ABIN7169301)

Target: PGAM5 (Phosphoglycerate Mutase Family Member 5 (PGAM5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGAM5 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-PGAM5 Antikörper (Biotin)

Bindungsspezifität: AA 30-223

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein phosphatase PGAM5, mitochondrial protein (30-223AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PGAM5

Target: PGAM5 (Phosphoglycerate Mutase Family Member 5 (PGAM5))

Andere Bezeichnung: PGAM5

Hintergrund:

Background: Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.

Aliases: Bcl-XL-binding protein v68 antibody, BXLBv68 antibody, MGC5352 antibody, mitochondrial antibody, PGAM5 antibody, PGAM5_HUMAN antibody, Phosphoglycerate mutase family member 5 antibody, Serine/threonine protein phosphatase PGAM5 mitochondrial antibody, Serine/threonine-protein phosphatase PGAM5 antibody

UniProt: Q96HS1