PGAM5 Antikörper (AA 30-225)
Kurzübersicht für PGAM5 Antikörper (AA 30-225) (ABIN7269317)
Target
Alle PGAM5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 30-225
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Verwendungszweck
- PGAM5 Rabbit pAb
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Sequenz
- KPRAGGDAEP RPAEPPAWAG GARPGPGVWD PNWDRREPLS LINVRKRNVE SGEEELASKL DHYKAKATRH IFLIRHSQYH VDGSLEKDRT LTPLGREQAE LTGLRLASLG LKFNKIVHSS MTRAIETTDI ISRHLPGVCK VSTDLLREGA PIEPDPPVSH WKPEAVQYYE DGARIEAAFR NYIHRADARQ EEDSYE
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-225 of human PGAM5 (NP_612642.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PGAM5 (Phosphoglycerate Mutase Family Member 5 (PGAM5))
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Andere Bezeichnung
- PGAM5
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Hintergrund
- Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.,PGAM5,BXLBV68,Signal Transduction,PGAM5
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Molekulargewicht
- 28kDa/32kDa
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Gen-ID
- 192111
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UniProt
- Q96HS1
Target
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