VRK1 Antikörper (AA 257-396)

Produktnummer ABIN7169217

Der Kaninchen Polyklonal Anti-VRK1-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, VRK1 in Proben von Human zu detektieren.

Kurzübersicht für VRK1 Antikörper (AA 257-396) (ABIN7169217)

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-VRK1 Antikörper

Bindungsspezifität: AA 257-396

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Serine/threonine-protein kinase VRK1 protein (257-396AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu VRK1

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Andere Bezeichnung: VRK1

Hintergrund:

Background: Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates \\\'Thr-18\\\' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.

Aliases: MGC117401 antibody, MGC138280 antibody, MGC142070 antibody, PCH1 antibody, PCH1A antibody, Serine/threonine protein kinase VRK1 antibody, Serine/threonine-protein kinase VRK1 antibody, Vaccinia related kinase 1 antibody, Vaccinia virus B1R related kinase 1 antibody, Vaccinia-related kinase 1 antibody, VRK1 antibody, VRK1_HUMAN antibody

UniProt: Q99986