RRM1 Antikörper

Produktnummer ABIN7168449

Der Maus Monoklonal Anti-RRM1-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, RRM1 in Proben von Human zu detektieren.

Kurzübersicht für RRM1 Antikörper (ABIN7168449)

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RRM1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Klon: 3D6H5

Produktdetails anti-RRM1 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Protein G purified

Immunogen: Recombinant Human RRM1 Protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution:IHC:1:50-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RRM1

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Andere Bezeichnung: RRM1

Hintergrund:

Background: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells.It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Aliases: Ribonucleotide Reductase M1,RRM1,RR1

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity