RBM38 Antikörper (AA 1-239)

Produktnummer ABIN7168341

Der Kaninchen Polyklonal Anti-RBM38-Antikörper wurde für ELISA, IHC und IF validiert. Er ist geeignet, RBM38 in Proben von Human zu detektieren.

Kurzübersicht für RBM38 Antikörper (AA 1-239) (ABIN7168341)

Target: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM38 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RBM38 Antikörper

Bindungsspezifität: AA 1-239

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human RNA-binding protein 38 protein (1-239AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RBM38

Target: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Andere Bezeichnung: RBM38

Hintergrund:

Background: RNA-binding protein that specifically bind the 3\'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.

Aliases: CLL associated antigen KW 5 antibody, CLL-associated antigen KW-5 antibody, HSRNASEB antibody, RBM38 antibody, RBM38_HUMAN antibody, RNA binding motif protein 38 antibody, RNA binding protein 38 antibody, RNA binding region (RNP1, RRM) containing 1 antibody, RNA binding region containing protein 1 antibody, RNA-binding motif protein 38 antibody, RNA-binding protein 38 antibody, RNA-binding region-containing protein 1 antibody, RNPC1 antibody, SEB4 antibody, SEB4B antibody, SEB4D antibody, ssDNA binding protein SEB4 antibody, ssDNA-binding protein SEB4 antibody

UniProt: Q9H0Z9

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development