MOV10L1 Antikörper (AA 336-425) (HRP)

Produktnummer ABIN7168294

Dieses Anti-MOV10L1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MOV10L1 in ELISA. Geeignet für Human.

Kurzübersicht für MOV10L1 Antikörper (AA 336-425) (HRP) (ABIN7168294)

Target: MOV10L1 (Mov10l1, Moloney Leukemia Virus 10-Like 1 (MOV10L1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MOV10L1 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-MOV10L1 Antikörper (HRP)

Bindungsspezifität: AA 336-425

Verwendungszweck: MOV10L1 Antibody, HRP conjugated

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human RNA helicase Mov10l1 protein (336-425AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MOV10L1

Target: MOV10L1 (Mov10l1, Moloney Leukemia Virus 10-Like 1 (MOV10L1))

Andere Bezeichnung: MOV10L1

Hintergrund:

Background: ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5\'-3\' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.

Aliases: Cardiac helicase activated by MEF2 protein antibody, Cardiac specific RNA helicase antibody, CHAMP antibody, Csm antibody, M10L1_HUMAN antibody, Moloney leukemia virus 10 like protein 1 antibody, Moloney leukemia virus 10-like protein 1 antibody, MOV10 like 1 antibody, MOV10 like protein 1 antibody, MOV10-like protein 1 antibody, MOV10L1 antibody, Mov10l1, Moloney leukemia virus 10 like 1, homolog (mouse) antibody, Putative helicase Mov10l1 antibody

UniProt: Q9BXT6