ARHGEF7 Antikörper (AA 1-250)

Produktnummer ABIN7167994

Produktdetails anti-ARHGEF7 Antikörper

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Bindungsspezifität: AA 1-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF7 Antikörper ist unkonjugiert

Applikation: ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Rho guanine nucleotide exchange factor 7 protein (1-250AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:200-1:500, IP:1:200-1:2000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ARHGEF7

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Andere Bezeichnung: ARHGEF7 (ARHGEF7 Produkte)

Hintergrund:

Background: Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions By similarity. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Aliases: ARHG7 antibody, ARHG7_HUMAN antibody, ARHGEF 7 antibody, Arhgef7 antibody, Beta pix antibody, Beta-Pix antibody, betaPix antibody, betaPix-b antibody, betaPix-c antibody, Cool antibody, COOL-1 antibody, COOL1 antibody, DKFZp686C12170 antibody, DKFZp761K1021 antibody, KIAA0142 antibody, KIAA0412 antibody, mKIAA0142 antibody, Nbla10314 antibody, P50 antibody, P50BP antibody, p85 antibody, P85COOL1 antibody, P85SPR antibody, PAK interacting exchange factor beta antibody, PAK-interacting exchange factor beta antibody, PAK3 antibody, Pak3bp antibody, PIX antibody, PIXB antibody, Rho guanine nucleotide exchange factor (GEF) 7 antibody, Rho guanine nucleotide exchange factor (GEF) 7b antibody, Rho guanine nucleotide exchange factor (GEF7) antibody, Rho guanine nucleotide exchange factor 7 antibody, SH3 domain containing proline rich protein antibody

UniProt: Q14155

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation