ARHGAP18 Antikörper (AA 389-577) (Biotin)

Produktnummer ABIN7167936

Der Kaninchen Polyklonal Anti-ARHGAP18-Antikörper wurde für ELISA validiert. Er ist geeignet, ARHGAP18 in Proben von Human zu detektieren.

Kurzübersicht für ARHGAP18 Antikörper (AA 389-577) (Biotin) (ABIN7167936)

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP18 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-ARHGAP18 Antikörper (Biotin)

Bindungsspezifität: AA 389-577

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Rho GTPase-activating protein 18 protein (389-577AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ARHGAP18

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Andere Bezeichnung: ARHGAP18

Hintergrund:

Background: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595).

Aliases: 4833419J07Rik antibody, AI314906 antibody, AI843501 antibody, Arhgap18 antibody, bA307O14.2 antibody, FLJ25728 antibody, MacGAP antibody, MGC126757 antibody, MGC138145 antibody, OTTHUMP00000017190 antibody, OTTMUSP00000028606 antibody, RHG18_HUMAN antibody, Rho GTPase-activating protein 18 antibody, Rho-type GTPase-activating protein 18 antibody, SENEX antibody

UniProt: Q8N392