ARHGAP18 Antikörper
Kurzübersicht für ARHGAP18 Antikörper (ABIN7075417)
Target
Alle ARHGAP18 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse ARHGAP18
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Applikationshinweise
- WB (H,M,R) 1:1000-1:1500, IHC/IF (M,R) 1:700-1:1400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))
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Andere Bezeichnung
- ARHGAP18
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Hintergrund
- Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1. Regulates cell shape, spreading, and migration.
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Molekulargewicht
- 75 kDa
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Gen-ID
- 73910
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NCBI Accession
- NP_789807
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UniProt
- Q8K0Q5
Target
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