ARHGAP18 Antikörper

Produktnummer ABIN7075417

Produktdetails anti-ARHGAP18 Antikörper

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse ARHGAP18

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1:1000-1:1500, IHC/IF (M,R) 1:700-1:1400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu ARHGAP18

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Andere Bezeichnung: ARHGAP18 (ARHGAP18 Produkte)

Synonyme: 4833419J07Rik antikoerper, AI314906 antikoerper, AI843501 antikoerper, MacGAP antikoerper, SENEX antikoerper, bA307O14.2 antikoerper, MGC146282 antikoerper, DKFZp469I1011 antikoerper, Rho GTPase activating protein 18 antikoerper, Rho GTPase activating protein 18 L homeolog antikoerper, Arhgap18 antikoerper, ARHGAP18 antikoerper, arhgap18 antikoerper, arhgap18.L antikoerper

Hintergrund: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1. Regulates cell shape, spreading, and migration.

Molekulargewicht: 75 kDa

Gen-ID: 73910

NCBI Accession: NP_789807

UniProt: Q8K0Q5