p107 Antikörper (AA 201-500)
Kurzübersicht für p107 Antikörper (AA 201-500) (ABIN7167787)
Target
Alle p107 (RBL1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 201-500
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Retinoblastoma-like protein 1 protein (201-500AA)
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Isotyp
- IgG
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anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibody
RBL1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB7537 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 905-1014) antibodyRBL1 Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 1A5 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1007-1035), (C-Term) antibodyRBL1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40387 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1-1014) antibodyRBL1 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (C-Term) antibodyRBL1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibodyRBL1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 100-200) antibodyRBL1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 143-192) antibodyRBL1 Reaktivität: Human, Maus, Rind (Kuh), Pferd, Schwein, Hund, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 935-984) antibodyRBL1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Fledermaus, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (N-Term) antibodyRBL1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Kaninchen, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Recommended dilution: WB:1:2000-1:5000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
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Andere Bezeichnung
- RBL1
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Hintergrund
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Background: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 \\\'Lys-20\\\' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.
Aliases: 107 kDa retinoblastoma-associated protein antibody, Cellular protein 107 antibody, Cellular protein p107 antibody, CP107 antibody, MGC40006 antibody, p107 antibody, PRB1 antibody, RBL1 antibody, RBL1_HUMAN antibody, Retinoblastoma like protein 1 antibody, retinoblastoma-like 1 (p107) antibody, Retinoblastoma-like protein 1 antibody
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UniProt
- P28749
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
Target
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