RENT2/UPF2 Antikörper (AA 1153-1272)

Produktnummer ABIN7167643

Dieses Anti-RENT2/UPF2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RENT2/UPF2 in IHC und ELISA. Geeignet für Human.

Kurzübersicht für RENT2/UPF2 Antikörper (AA 1153-1272) (ABIN7167643)

Target: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RENT2/UPF2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-RENT2/UPF2 Antikörper

Bindungsspezifität: AA 1153-1272

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Regulator of nonsense transcripts 2 protein (1153-1272AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RENT2/UPF2

Target: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Andere Bezeichnung: UPF2

Hintergrund:

Background: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA.

Aliases: DKFZp434D222 antibody, hUpf2 antibody, KIAA1408 antibody, MGC138834 antibody, MGC138835 antibody, Nonsense mRNA reducing factor 2 antibody, Regulator of nonsense transcripts 2 antibody, RENT2 antibody, RENT2_HUMAN antibody, Smg 3 antibody, Smg 3 homolog nonsense mediated mRNA decay factor antibody, Up-frameshift suppressor 2 homolog antibody, UPF2 antibody, UPF2 regulator of nonsense transcripts homolog antibody, UROC1 antibody, Urocanate hydratase antibody, Yeast Upf2p homolog antibody

UniProt: Q9HAU5