RMI1 Antikörper (AA 181-443)

Produktnummer ABIN7167546

Der Kaninchen Polyklonal anti-RMI1 Antikörper wird verwendet zum Nachweis von RMI1 in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für RMI1 Antikörper (AA 181-443) (ABIN7167546)

Target: RMI1 (Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RMI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RMI1 Antikörper

Bindungsspezifität: AA 181-443

Verwendungszweck: RMI1 Antibody

Kreuzreaktivität: Maus

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human RecQ-mediated genome instability protein 1 protein (181-443AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RMI1

Target: RMI1 (Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1))

Andere Bezeichnung: RMI1

Hintergrund:

Background: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.

Aliases: BLAP75 antibody, BLM associated polypeptide 75 kDa antibody, BLM associated protein 75 kDa antibody, BLM-associated protein of 75 kDa antibody, C9orf76 antibody, FAAP75 antibody, FLJ12888 antibody, Homolog of yeast RecQ mediated genome instability 1 antibody, RecQ mediated genome instability 1 antibody, RecQ-mediated genome instability protein 1 antibody, Rmi1 antibody, RMI1 homolog antibody, RMI1 RecQ mediated genome instability 1 homolog antibody, RMI1_HUMAN antibody, RP11-346I8 antibody

UniProt: Q9H9A7

Pathways: DNA Reparatur