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REST Antikörper (AA 250-350)

This anti-REST antibody (ABIN7167425) is a Rabbit Polyclonal antibody detecting REST in ELISA, IF. Suitable for Human.
Produktnummer ABIN7167425

Kurzübersicht für REST Antikörper (AA 250-350) (ABIN7167425)

Target

Alle REST Antikörper anzeigen
REST (RE1-Silencing Transcription Factor (REST))

Reaktivität

  • 44
  • 10
  • 8
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 43
  • 1
Kaninchen

Klonalität

  • 42
  • 2
Polyklonal

Konjugat

  • 26
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser REST Antikörper ist unkonjugiert

Applikation

  • 30
  • 18
  • 10
  • 8
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Immunofluorescence (IF)
  • Bindungsspezifität

    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-350

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human RE1-silencing transcription factor protein (250-350AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: IF:1:50-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    REST (RE1-Silencing Transcription Factor (REST))

    Andere Bezeichnung

    REST

    Hintergrund

    Background: Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression.

    Aliases: Neural Restrictive Silencer Factor antibody, Neural-restrictive silencer factor antibody, Neuron Restrictive Silencer Factor antibody, NRSF antibody, RE1 silencing transcription factor antibody, RE1-silencing transcription factor antibody, Repressor binding to the X2 box antibody, rest antibody, REST protein antibody, REST_HUMAN antibody, X2 box repressor antibody, XBR antibody

    UniProt

    Q13127

    Pathways

    Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
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