SYNGAP1 Antikörper (AA 1161-1343)

Produktnummer ABIN7167409

Produktdetails anti-SYNGAP1 Antikörper

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Bindungsspezifität: AA 1161-1343

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYNGAP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ras/Rap GTPase-activating protein SynGAP protein (1161-1343AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SYNGAP1

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Andere Bezeichnung: SYNGAP1 (SYNGAP1 Produkte)

Hintergrund:

Background: Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).

Aliases: DKFZp761G1421 antibody, KIAA1938 antibody, MRD5 antibody, Neuronal RasGAP antibody, OTTHUMP00000064825 antibody, p135 SynGAP antibody, Ras GTPase activating protein SynGAP antibody, Ras GTPase-activating protein SynGAP antibody, RASA 1 antibody, RASA 5 antibody, RASA1 antibody, RASA5 antibody, SYGP1_HUMAN antibody, Synaptic Ras GAP 1 antibody, Synaptic Ras GTPase activating protein 1 antibody, Synaptic Ras GTPase activating protein 1 homolog antibody, Synaptic Ras GTPase activating protein 135 kDa antibody, Synaptic Ras GTPase activating protein antibody, Synaptic Ras GTPase-activating protein 1 antibody, Synaptic Ras-GAP 1 antibody, SYNGAP 1 antibody, SYNGAP1 antibody

UniProt: Q96PV0

Pathways: Regulation of long-term Neuronal Synaptic Plasticity