SYNGAP1 Antikörper (AA 1161-1343)
Kurzübersicht für SYNGAP1 Antikörper (AA 1161-1343) (ABIN7167409)
Target
Alle SYNGAP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1161-1343
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Ras/Rap GTPase-activating protein SynGAP protein (1161-1343AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IF:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
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Andere Bezeichnung
- SYNGAP1
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Hintergrund
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Background: Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).
Aliases: DKFZp761G1421 antibody, KIAA1938 antibody, MRD5 antibody, Neuronal RasGAP antibody, OTTHUMP00000064825 antibody, p135 SynGAP antibody, Ras GTPase activating protein SynGAP antibody, Ras GTPase-activating protein SynGAP antibody, RASA 1 antibody, RASA 5 antibody, RASA1 antibody, RASA5 antibody, SYGP1_HUMAN antibody, Synaptic Ras GAP 1 antibody, Synaptic Ras GTPase activating protein 1 antibody, Synaptic Ras GTPase activating protein 1 homolog antibody, Synaptic Ras GTPase activating protein 135 kDa antibody, Synaptic Ras GTPase activating protein antibody, Synaptic Ras GTPase-activating protein 1 antibody, Synaptic Ras-GAP 1 antibody, SYNGAP 1 antibody, SYNGAP1 antibody
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UniProt
- Q96PV0
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Pathways
- Regulation of long-term Neuronal Synaptic Plasticity
Target
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