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SYNGAP1 Antikörper (AA 1161-1343)

Dieses Anti-SYNGAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SYNGAP1 in ELISA und IF. Geeignet für Human.
Produktnummer ABIN7167409

Kurzübersicht für SYNGAP1 Antikörper (AA 1161-1343) (ABIN7167409)

Target

Alle SYNGAP1 Antikörper anzeigen
SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Reaktivität

  • 18
  • 10
  • 9
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 18
  • 2
Kaninchen

Klonalität

  • 16
  • 4
Polyklonal

Konjugat

  • 17
  • 1
  • 1
  • 1
Dieser SYNGAP1 Antikörper ist unkonjugiert

Applikation

  • 17
  • 10
  • 6
  • 5
  • 4
  • 3
  • 2
ELISA, Immunofluorescence (IF)
  • Bindungsspezifität

    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1161-1343

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Ras/Rap GTPase-activating protein SynGAP protein (1161-1343AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: IF:1:50-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

    Andere Bezeichnung

    SYNGAP1

    Hintergrund

    Background: Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).

    Aliases: DKFZp761G1421 antibody, KIAA1938 antibody, MRD5 antibody, Neuronal RasGAP antibody, OTTHUMP00000064825 antibody, p135 SynGAP antibody, Ras GTPase activating protein SynGAP antibody, Ras GTPase-activating protein SynGAP antibody, RASA 1 antibody, RASA 5 antibody, RASA1 antibody, RASA5 antibody, SYGP1_HUMAN antibody, Synaptic Ras GAP 1 antibody, Synaptic Ras GTPase activating protein 1 antibody, Synaptic Ras GTPase activating protein 1 homolog antibody, Synaptic Ras GTPase activating protein 135 kDa antibody, Synaptic Ras GTPase activating protein antibody, Synaptic Ras GTPase-activating protein 1 antibody, Synaptic Ras-GAP 1 antibody, SYNGAP 1 antibody, SYNGAP1 antibody

    UniProt

    Q96PV0

    Pathways

    Regulation of long-term Neuronal Synaptic Plasticity
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